Cargando…
Exploring the alpha‐gliadin locus: the 33‐mer peptide with six overlapping coeliac disease epitopes in Triticum aestivum is derived from a subgroup of Aegilops tauschii
Most alpha‐gliadin genes of the Gli‐D2 locus on the D genome of hexaploid bread wheat (Triticum aestivum) encode for proteins with epitopes that can trigger coeliac disease (CD), and several contain a 33‐mer peptide with six partly overlapping copies of three epitopes, which is regarded as a remarka...
Autores principales: | Schaart, Jan G., Salentijn, Elma M. J., Goryunova, Svetlana V., Chidzanga, Charity, Esselink, Danny G., Gosman, Nick, Bentley, Alison R., Gilissen, Luud J. W. J., Smulders, Marinus J. M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248119/ https://www.ncbi.nlm.nih.gov/pubmed/33369792 http://dx.doi.org/10.1111/tpj.15147 |
Ejemplares similares
-
Expansion of the gamma-gliadin gene family in Aegilops and Triticum
por: Goryunova, Svetlana V, et al.
Publicado: (2012) -
Celiac disease T-cell epitopes from gamma-gliadins: immunoreactivity depends on the genome of origin, transcript frequency, and flanking protein variation
por: Salentijn, Elma MJ, et al.
Publicado: (2012) -
Tetraploid and hexaploid wheat varieties reveal large differences in expression of alpha-gliadins from homoeologous Gli-2 loci
por: Salentijn, Elma MJ, et al.
Publicado: (2009) -
Quantitative and qualitative differences in celiac disease epitopes among durum wheat varieties identified through deep RNA-amplicon sequencing
por: Salentijn, Elma MJ, et al.
Publicado: (2013) -
A Universal Approach to Eliminate Antigenic Properties of Alpha-Gliadin Peptides in Celiac Disease
por: Mitea, Cristina, et al.
Publicado: (2010)