Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein

α-synuclein (αSyn) is the main protein component of Lewy bodies, intracellular inclusions found in the brain of Parkinson’s disease (PD) patients. Neurotoxic αSyn species are broadly modified post-translationally and, in patients with genetic forms of PD, carry genetically encoded amino acid substit...

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Detalles Bibliográficos
Autores principales: Martinez Hernandez, Ana, Silbern, Ivan, Geffers, Insa, Tatenhorst, Lars, Becker, Stefan, Urlaub, Henning, Zweckstetter, Markus, Griesinger, Christian, Eichele, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248494/
https://www.ncbi.nlm.nih.gov/pubmed/34220415
http://dx.doi.org/10.3389/fnins.2021.643391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248494/
https://www.ncbi.nlm.nih.gov/pubmed/34220415
http://dx.doi.org/10.3389/fnins.2021.643391

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