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Humanized Mouse Models for the Study of Periodontitis: An Opportunity to Elucidate Unresolved Aspects of Its Immunopathogenesis and Analyze New Immunotherapeutic Strategies

Periodontitis is an oral inflammatory disease in which the polymicrobial synergy and dysbiosis of the subgingival microbiota trigger a deregulated host immune response, that leads to the breakdown of tooth-supporting tissues and finally tooth loss. Periodontitis is characterized by the increased pat...

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Detalles Bibliográficos
Autores principales: Rojas, Carolina, García, Michelle P., Polanco, Alan F., González-Osuna, Luis, Sierra-Cristancho, Alfredo, Melgar-Rodríguez, Samanta, Cafferata, Emilio A., Vernal, Rolando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248545/
https://www.ncbi.nlm.nih.gov/pubmed/34220811
http://dx.doi.org/10.3389/fimmu.2021.663328