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Humanized Mouse Models for the Study of Periodontitis: An Opportunity to Elucidate Unresolved Aspects of Its Immunopathogenesis and Analyze New Immunotherapeutic Strategies
Periodontitis is an oral inflammatory disease in which the polymicrobial synergy and dysbiosis of the subgingival microbiota trigger a deregulated host immune response, that leads to the breakdown of tooth-supporting tissues and finally tooth loss. Periodontitis is characterized by the increased pat...
Autores principales: | Rojas, Carolina, García, Michelle P., Polanco, Alan F., González-Osuna, Luis, Sierra-Cristancho, Alfredo, Melgar-Rodríguez, Samanta, Cafferata, Emilio A., Vernal, Rolando |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248545/ https://www.ncbi.nlm.nih.gov/pubmed/34220811 http://dx.doi.org/10.3389/fimmu.2021.663328 |
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