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9-Gene Signature Correlated With CD8(+) T Cell Infiltration Activated by IFN-γ: A Biomarker of Immune Checkpoint Therapy Response in Melanoma

PURPOSE: To identify CD8(+) T cell-related factors and the co-expression network in melanoma and illustrate the interactions among CD8(+) T cell-related genes in the melanoma tumor microenvironment. METHOD: We obtained melanoma and paracancerous tissue mRNA matrices from TCGA-SKCM and GSE65904. The...

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Detalles Bibliográficos
Autores principales:	Yan, Kexin, Lu, Yuxiu, Yan, Zhangyong, Wang, Yutao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248551/ https://www.ncbi.nlm.nih.gov/pubmed/34220795 http://dx.doi.org/10.3389/fimmu.2021.622563

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