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Dealing with uncertainty: A high-density EEG investigation on how intolerance of uncertainty affects emotional predictions

Intolerance of uncertainty (IU) can influence emotional predictions, constructed by the brain (generation stage) to prearrange action (implementation stage), and update internal models according to incoming stimuli (updating stage). However, neurocomputational mechanisms by which IU affects emotiona...

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Autores principales: Del Popolo Cristaldi, Fiorella, Mento, Giovanni, Sarlo, Michela, Buodo, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248604/
https://www.ncbi.nlm.nih.gov/pubmed/34197554
http://dx.doi.org/10.1371/journal.pone.0254045
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author Del Popolo Cristaldi, Fiorella
Mento, Giovanni
Sarlo, Michela
Buodo, Giulia
author_facet Del Popolo Cristaldi, Fiorella
Mento, Giovanni
Sarlo, Michela
Buodo, Giulia
author_sort Del Popolo Cristaldi, Fiorella
collection PubMed
description Intolerance of uncertainty (IU) can influence emotional predictions, constructed by the brain (generation stage) to prearrange action (implementation stage), and update internal models according to incoming stimuli (updating stage). However, neurocomputational mechanisms by which IU affects emotional predictions are unclear. This high-density EEG study investigated if IU predicted event-related potentials (ERPs) and brain sources activity developing along the stages of emotional predictions, as a function of contextual uncertainty. Thirty-six undergraduates underwent a S1-S2 paradigm, with emotional faces and pictures as S1s and S2s, respectively. Contextual uncertainty was manipulated across three blocks, each with 100%, 75%, or 50% S1-S2 emotional congruency. ERPs, brain sources and their relationship with IU scores were analyzed for each stage. IU did not affect prediction generation. During prediction implementation, higher IU predicted larger Contingent Negative Variation in the 75% block, and lower left anterior cingulate cortex and supplementary motor area activations. During prediction updating, as IU increased P2 to positive S2s decreased, along with P2 and Late Positive Potential in the 75% block, and right orbito-frontal cortex activity to emotional S2s. IU was therefore associated with altered uncertainty assessment and heightened attention deployment during implementation, and to uncertainty avoidance, reduced attention to safety cues and disrupted access to emotion regulation strategies during prediction updating.
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spelling pubmed-82486042021-07-09 Dealing with uncertainty: A high-density EEG investigation on how intolerance of uncertainty affects emotional predictions Del Popolo Cristaldi, Fiorella Mento, Giovanni Sarlo, Michela Buodo, Giulia PLoS One Research Article Intolerance of uncertainty (IU) can influence emotional predictions, constructed by the brain (generation stage) to prearrange action (implementation stage), and update internal models according to incoming stimuli (updating stage). However, neurocomputational mechanisms by which IU affects emotional predictions are unclear. This high-density EEG study investigated if IU predicted event-related potentials (ERPs) and brain sources activity developing along the stages of emotional predictions, as a function of contextual uncertainty. Thirty-six undergraduates underwent a S1-S2 paradigm, with emotional faces and pictures as S1s and S2s, respectively. Contextual uncertainty was manipulated across three blocks, each with 100%, 75%, or 50% S1-S2 emotional congruency. ERPs, brain sources and their relationship with IU scores were analyzed for each stage. IU did not affect prediction generation. During prediction implementation, higher IU predicted larger Contingent Negative Variation in the 75% block, and lower left anterior cingulate cortex and supplementary motor area activations. During prediction updating, as IU increased P2 to positive S2s decreased, along with P2 and Late Positive Potential in the 75% block, and right orbito-frontal cortex activity to emotional S2s. IU was therefore associated with altered uncertainty assessment and heightened attention deployment during implementation, and to uncertainty avoidance, reduced attention to safety cues and disrupted access to emotion regulation strategies during prediction updating. Public Library of Science 2021-07-01 /pmc/articles/PMC8248604/ /pubmed/34197554 http://dx.doi.org/10.1371/journal.pone.0254045 Text en © 2021 Del Popolo Cristaldi et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Del Popolo Cristaldi, Fiorella
Mento, Giovanni
Sarlo, Michela
Buodo, Giulia
Dealing with uncertainty: A high-density EEG investigation on how intolerance of uncertainty affects emotional predictions
title Dealing with uncertainty: A high-density EEG investigation on how intolerance of uncertainty affects emotional predictions
title_full Dealing with uncertainty: A high-density EEG investigation on how intolerance of uncertainty affects emotional predictions
title_fullStr Dealing with uncertainty: A high-density EEG investigation on how intolerance of uncertainty affects emotional predictions
title_full_unstemmed Dealing with uncertainty: A high-density EEG investigation on how intolerance of uncertainty affects emotional predictions
title_short Dealing with uncertainty: A high-density EEG investigation on how intolerance of uncertainty affects emotional predictions
title_sort dealing with uncertainty: a high-density eeg investigation on how intolerance of uncertainty affects emotional predictions
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248604/
https://www.ncbi.nlm.nih.gov/pubmed/34197554
http://dx.doi.org/10.1371/journal.pone.0254045
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