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The genetic association of the transcription factor NPAT with glycemic response to metformin involves regulation of fuel selection

The biguanide, metformin, is the first-choice therapeutic agent for type-2 diabetes, although the mechanisms that underpin metformin clinical efficacy remain the subject of much debate, partly due to the considerable variation in patient response to metformin. Identification of poor responders by ge...

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Detalles Bibliográficos
Autores principales:	Chen, Changwei, Gallagher, Jennifer R., Tarlton, Jamie, van Aalten, Lidy, Bray, Susan E., Ashford, Michael L. J., McCrimmon, Rory J., Pearson, Ewan R., McNeilly, Alison D., Sutherland, Calum
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248654/ https://www.ncbi.nlm.nih.gov/pubmed/34197485 http://dx.doi.org/10.1371/journal.pone.0253533

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