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HIV-1 Gag gene mutations, treatment response and drug resistance to protease inhibitors: A systematic review and meta-analysis protocol

BACKGROUND: Some mutations in the HIV-1 Gag gene are known to confer resistance to ritonavir-boosted protease inhibitors (PI/r), but their clinical implications remain controversial. This review aims at summarizing current knowledge on HIV-1 Gag gene mutations that are selected under PI/r pressure a...

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Detalles Bibliográficos
Autores principales: Nka, Alex Durand, Teto, Georges, Santoro, Maria Mercedes, Ngum Ndze, Valantine, Takou, Désiré, Dambaya, Beatrice, Ngoufack Jagni Semengue, Ezechiel, Fabeni, Lavinia, Perno, Carlo-Federico, Colizzi, Vittorio, Ceccherini-Silberstein, Francesca, Fokam, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248685/
https://www.ncbi.nlm.nih.gov/pubmed/34197501
http://dx.doi.org/10.1371/journal.pone.0253587