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PKCδ deficiency inhibits fetal development and is associated with heart elastic fiber hyperplasia and lung inflammation in adult PKCδ knockout mice
Protein kinase C-delta (PKCδ) has a caspase-3 recognition sequence in its structure, suggesting its involvement in apoptosis. In addition, PKCδ was recently reported to function as an anti-cancer factor. The generation of a PKCδ knockout mouse model indicated that PKCδ plays a role in B cell homeost...
Autores principales: | Niino, Yuko S., Kawashima, Ikuo, Iguchi, Yoshinobu, Kanda, Hiroaki, Ogura, Kiyoshi, Mita-Yoshida, Kaoru, Ono, Tomio, Yamazaki, Maya, Sakimura, Kenji, Yogosawa, Satomi, Yoshida, Kiyotsugu, Shioda, Seiji, Gotoh, Takaya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248728/ https://www.ncbi.nlm.nih.gov/pubmed/34197550 http://dx.doi.org/10.1371/journal.pone.0253912 |
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