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Genetic Deletion of mGlu3 Metabotropic Glutamate Receptors Amplifies Ischemic Brain Damage and Associated Neuroinflammation in Mice

Backgroud: Type-3 metabotropic glutamate (mGlu3) receptors are found in both neurons and glial cells and regulate synaptic transmission, astrocyte function, and microglial reactivity. Here we show that the genetic deletion of mGlu3 receptors amplifies ischemic brain damage and associated neuroinflam...

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Detalles Bibliográficos
Autores principales:	Mastroiacovo, Federica, Zinni, Manuela, Mascio, Giada, Bruno, Valeria, Battaglia, Giuseppe, Pansiot, Julien, Imbriglio, Tiziana, Mairesse, Jerome, Baud, Olivier, Nicoletti, Ferdinando
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248796/ https://www.ncbi.nlm.nih.gov/pubmed/34220677 http://dx.doi.org/10.3389/fneur.2021.668877

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