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Enhanced IL-1β Release Following NLRP3 and AIM2 Inflammasome Stimulation Is Linked to mtROS in Airway Macrophages in Pulmonary Fibrosis

Fibrotic Interstitial lung diseases (ILDs) are complex disorders of variable clinical behaviour. The majority of them cause significant morbidity, whilst Idiopathic Pulmonary Fibrosis (IPF) is recognised as the most relentless. NLRP3, AIM2, and NLRC4 inflammasomes are multiprotein complexes driving...

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Detalles Bibliográficos
Autores principales:	Trachalaki, Athina, Tsitoura, Eliza, Mastrodimou, Semeli, Invernizzi, Rachele, Vasarmidi, Eirini, Bibaki, Eleni, Tzanakis, Nikolaos, Molyneaux, Philip L., Maher, Toby M., Antoniou, Katerina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248801/ https://www.ncbi.nlm.nih.gov/pubmed/34220810 http://dx.doi.org/10.3389/fimmu.2021.661811

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