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Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila

To advance our understanding of adaptation to temporally varying selection pressures, we identified signatures of seasonal adaptation occurring in parallel among Drosophila melanogaster populations. Specifically, we estimated allele frequencies genome-wide from flies sampled early and late in the gr...

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Autores principales: Machado, Heather E, Bergland, Alan O, Taylor, Ryan, Tilk, Susanne, Behrman, Emily, Dyer, Kelly, Fabian, Daniel K, Flatt, Thomas, González, Josefa, Karasov, Talia L, Kim, Bernard, Kozeretska, Iryna, Lazzaro, Brian P, Merritt, Thomas JS, Pool, John E, O'Brien, Katherine, Rajpurohit, Subhash, Roy, Paula R, Schaeffer, Stephen W, Serga, Svitlana, Schmidt, Paul, Petrov, Dmitri A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248982/
https://www.ncbi.nlm.nih.gov/pubmed/34155971
http://dx.doi.org/10.7554/eLife.67577
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author Machado, Heather E
Bergland, Alan O
Taylor, Ryan
Tilk, Susanne
Behrman, Emily
Dyer, Kelly
Fabian, Daniel K
Flatt, Thomas
González, Josefa
Karasov, Talia L
Kim, Bernard
Kozeretska, Iryna
Lazzaro, Brian P
Merritt, Thomas JS
Pool, John E
O'Brien, Katherine
Rajpurohit, Subhash
Roy, Paula R
Schaeffer, Stephen W
Serga, Svitlana
Schmidt, Paul
Petrov, Dmitri A
author_facet Machado, Heather E
Bergland, Alan O
Taylor, Ryan
Tilk, Susanne
Behrman, Emily
Dyer, Kelly
Fabian, Daniel K
Flatt, Thomas
González, Josefa
Karasov, Talia L
Kim, Bernard
Kozeretska, Iryna
Lazzaro, Brian P
Merritt, Thomas JS
Pool, John E
O'Brien, Katherine
Rajpurohit, Subhash
Roy, Paula R
Schaeffer, Stephen W
Serga, Svitlana
Schmidt, Paul
Petrov, Dmitri A
author_sort Machado, Heather E
collection PubMed
description To advance our understanding of adaptation to temporally varying selection pressures, we identified signatures of seasonal adaptation occurring in parallel among Drosophila melanogaster populations. Specifically, we estimated allele frequencies genome-wide from flies sampled early and late in the growing season from 20 widely dispersed populations. We identified parallel seasonal allele frequency shifts across North America and Europe, demonstrating that seasonal adaptation is a general phenomenon of temperate fly populations. Seasonally fluctuating polymorphisms are enriched in large chromosomal inversions, and we find a broad concordance between seasonal and spatial allele frequency change. The direction of allele frequency change at seasonally variable polymorphisms can be predicted by weather conditions in the weeks prior to sampling, linking the environment and the genomic response to selection. Our results suggest that fluctuating selection is an important evolutionary force affecting patterns of genetic variation in Drosophila.
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spelling pubmed-82489822021-07-02 Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila Machado, Heather E Bergland, Alan O Taylor, Ryan Tilk, Susanne Behrman, Emily Dyer, Kelly Fabian, Daniel K Flatt, Thomas González, Josefa Karasov, Talia L Kim, Bernard Kozeretska, Iryna Lazzaro, Brian P Merritt, Thomas JS Pool, John E O'Brien, Katherine Rajpurohit, Subhash Roy, Paula R Schaeffer, Stephen W Serga, Svitlana Schmidt, Paul Petrov, Dmitri A eLife Ecology To advance our understanding of adaptation to temporally varying selection pressures, we identified signatures of seasonal adaptation occurring in parallel among Drosophila melanogaster populations. Specifically, we estimated allele frequencies genome-wide from flies sampled early and late in the growing season from 20 widely dispersed populations. We identified parallel seasonal allele frequency shifts across North America and Europe, demonstrating that seasonal adaptation is a general phenomenon of temperate fly populations. Seasonally fluctuating polymorphisms are enriched in large chromosomal inversions, and we find a broad concordance between seasonal and spatial allele frequency change. The direction of allele frequency change at seasonally variable polymorphisms can be predicted by weather conditions in the weeks prior to sampling, linking the environment and the genomic response to selection. Our results suggest that fluctuating selection is an important evolutionary force affecting patterns of genetic variation in Drosophila. eLife Sciences Publications, Ltd 2021-06-22 /pmc/articles/PMC8248982/ /pubmed/34155971 http://dx.doi.org/10.7554/eLife.67577 Text en © 2021, Machado et al https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Ecology
Machado, Heather E
Bergland, Alan O
Taylor, Ryan
Tilk, Susanne
Behrman, Emily
Dyer, Kelly
Fabian, Daniel K
Flatt, Thomas
González, Josefa
Karasov, Talia L
Kim, Bernard
Kozeretska, Iryna
Lazzaro, Brian P
Merritt, Thomas JS
Pool, John E
O'Brien, Katherine
Rajpurohit, Subhash
Roy, Paula R
Schaeffer, Stephen W
Serga, Svitlana
Schmidt, Paul
Petrov, Dmitri A
Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila
title Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila
title_full Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila
title_fullStr Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila
title_full_unstemmed Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila
title_short Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila
title_sort broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in drosophila
topic Ecology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248982/
https://www.ncbi.nlm.nih.gov/pubmed/34155971
http://dx.doi.org/10.7554/eLife.67577
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