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Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila
To advance our understanding of adaptation to temporally varying selection pressures, we identified signatures of seasonal adaptation occurring in parallel among Drosophila melanogaster populations. Specifically, we estimated allele frequencies genome-wide from flies sampled early and late in the gr...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248982/ https://www.ncbi.nlm.nih.gov/pubmed/34155971 http://dx.doi.org/10.7554/eLife.67577 |
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author | Machado, Heather E Bergland, Alan O Taylor, Ryan Tilk, Susanne Behrman, Emily Dyer, Kelly Fabian, Daniel K Flatt, Thomas González, Josefa Karasov, Talia L Kim, Bernard Kozeretska, Iryna Lazzaro, Brian P Merritt, Thomas JS Pool, John E O'Brien, Katherine Rajpurohit, Subhash Roy, Paula R Schaeffer, Stephen W Serga, Svitlana Schmidt, Paul Petrov, Dmitri A |
author_facet | Machado, Heather E Bergland, Alan O Taylor, Ryan Tilk, Susanne Behrman, Emily Dyer, Kelly Fabian, Daniel K Flatt, Thomas González, Josefa Karasov, Talia L Kim, Bernard Kozeretska, Iryna Lazzaro, Brian P Merritt, Thomas JS Pool, John E O'Brien, Katherine Rajpurohit, Subhash Roy, Paula R Schaeffer, Stephen W Serga, Svitlana Schmidt, Paul Petrov, Dmitri A |
author_sort | Machado, Heather E |
collection | PubMed |
description | To advance our understanding of adaptation to temporally varying selection pressures, we identified signatures of seasonal adaptation occurring in parallel among Drosophila melanogaster populations. Specifically, we estimated allele frequencies genome-wide from flies sampled early and late in the growing season from 20 widely dispersed populations. We identified parallel seasonal allele frequency shifts across North America and Europe, demonstrating that seasonal adaptation is a general phenomenon of temperate fly populations. Seasonally fluctuating polymorphisms are enriched in large chromosomal inversions, and we find a broad concordance between seasonal and spatial allele frequency change. The direction of allele frequency change at seasonally variable polymorphisms can be predicted by weather conditions in the weeks prior to sampling, linking the environment and the genomic response to selection. Our results suggest that fluctuating selection is an important evolutionary force affecting patterns of genetic variation in Drosophila. |
format | Online Article Text |
id | pubmed-8248982 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | eLife Sciences Publications, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-82489822021-07-02 Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila Machado, Heather E Bergland, Alan O Taylor, Ryan Tilk, Susanne Behrman, Emily Dyer, Kelly Fabian, Daniel K Flatt, Thomas González, Josefa Karasov, Talia L Kim, Bernard Kozeretska, Iryna Lazzaro, Brian P Merritt, Thomas JS Pool, John E O'Brien, Katherine Rajpurohit, Subhash Roy, Paula R Schaeffer, Stephen W Serga, Svitlana Schmidt, Paul Petrov, Dmitri A eLife Ecology To advance our understanding of adaptation to temporally varying selection pressures, we identified signatures of seasonal adaptation occurring in parallel among Drosophila melanogaster populations. Specifically, we estimated allele frequencies genome-wide from flies sampled early and late in the growing season from 20 widely dispersed populations. We identified parallel seasonal allele frequency shifts across North America and Europe, demonstrating that seasonal adaptation is a general phenomenon of temperate fly populations. Seasonally fluctuating polymorphisms are enriched in large chromosomal inversions, and we find a broad concordance between seasonal and spatial allele frequency change. The direction of allele frequency change at seasonally variable polymorphisms can be predicted by weather conditions in the weeks prior to sampling, linking the environment and the genomic response to selection. Our results suggest that fluctuating selection is an important evolutionary force affecting patterns of genetic variation in Drosophila. eLife Sciences Publications, Ltd 2021-06-22 /pmc/articles/PMC8248982/ /pubmed/34155971 http://dx.doi.org/10.7554/eLife.67577 Text en © 2021, Machado et al https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited. |
spellingShingle | Ecology Machado, Heather E Bergland, Alan O Taylor, Ryan Tilk, Susanne Behrman, Emily Dyer, Kelly Fabian, Daniel K Flatt, Thomas González, Josefa Karasov, Talia L Kim, Bernard Kozeretska, Iryna Lazzaro, Brian P Merritt, Thomas JS Pool, John E O'Brien, Katherine Rajpurohit, Subhash Roy, Paula R Schaeffer, Stephen W Serga, Svitlana Schmidt, Paul Petrov, Dmitri A Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila |
title | Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila |
title_full | Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila |
title_fullStr | Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila |
title_full_unstemmed | Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila |
title_short | Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila |
title_sort | broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in drosophila |
topic | Ecology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8248982/ https://www.ncbi.nlm.nih.gov/pubmed/34155971 http://dx.doi.org/10.7554/eLife.67577 |
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