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Larger Chondral Lesions Treated with Collagen Membrane – Matrix-Induced Autologous Chondrogenesis – Show Larger Increase in Clinical Scores

Objective  To evaluate clinically and radiologically the results of the treatment of chondral lesions using collagen membrane - autologous matrix-induced chondrogenesis (AMIC). Methods  This is a series of observational cases, in which 15 patients undergoing AMIC were analyzed. The clinical evaluati...

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Autores principales: Miyahira, Mateus Kenji Christo, Novaretti, João Victor, Astur, Diego Costa, Kaleka, Camila Cohen, Amaro, Joicemar Tarouco, Cohen, Moisés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Revinter Publicações Ltda. 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249057/
https://www.ncbi.nlm.nih.gov/pubmed/34239198
http://dx.doi.org/10.1055/s-0040-1712493
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author Miyahira, Mateus Kenji Christo
Novaretti, João Victor
Astur, Diego Costa
Kaleka, Camila Cohen
Amaro, Joicemar Tarouco
Cohen, Moisés
author_facet Miyahira, Mateus Kenji Christo
Novaretti, João Victor
Astur, Diego Costa
Kaleka, Camila Cohen
Amaro, Joicemar Tarouco
Cohen, Moisés
author_sort Miyahira, Mateus Kenji Christo
collection PubMed
description Objective  To evaluate clinically and radiologically the results of the treatment of chondral lesions using collagen membrane - autologous matrix-induced chondrogenesis (AMIC). Methods  This is a series of observational cases, in which 15 patients undergoing AMIC were analyzed. The clinical evaluation was made by comparing the Lysholm and International Knee Document Commitee (IKDC) scores in the pre- and postoperative period of 12 months, and radiological evaluation using the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score in the same postoperative period. Results  The mean age of the patients was 39.2 years old, and the mean size of the chondral lesions was 1.55cm (2) . There was a significant improvement in clinical scores, with a mean increase of 24.6 points on Lysholm and of 24.3 on IKDC after 12 months. In the radiological evaluation, MOCART had a mean of 65 points. It was observed that the larger the size of the lesion, the greater the improvement in scores. Conclusion  Evaluating subjective clinical scores, the treatment of chondral lesions with the collagen membrane showed good results, as well as the evaluation of MOCART, with greater benefit in larger lesions.
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spelling pubmed-82490572021-07-07 Larger Chondral Lesions Treated with Collagen Membrane – Matrix-Induced Autologous Chondrogenesis – Show Larger Increase in Clinical Scores Miyahira, Mateus Kenji Christo Novaretti, João Victor Astur, Diego Costa Kaleka, Camila Cohen Amaro, Joicemar Tarouco Cohen, Moisés Rev Bras Ortop (Sao Paulo) Objective  To evaluate clinically and radiologically the results of the treatment of chondral lesions using collagen membrane - autologous matrix-induced chondrogenesis (AMIC). Methods  This is a series of observational cases, in which 15 patients undergoing AMIC were analyzed. The clinical evaluation was made by comparing the Lysholm and International Knee Document Commitee (IKDC) scores in the pre- and postoperative period of 12 months, and radiological evaluation using the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score in the same postoperative period. Results  The mean age of the patients was 39.2 years old, and the mean size of the chondral lesions was 1.55cm (2) . There was a significant improvement in clinical scores, with a mean increase of 24.6 points on Lysholm and of 24.3 on IKDC after 12 months. In the radiological evaluation, MOCART had a mean of 65 points. It was observed that the larger the size of the lesion, the greater the improvement in scores. Conclusion  Evaluating subjective clinical scores, the treatment of chondral lesions with the collagen membrane showed good results, as well as the evaluation of MOCART, with greater benefit in larger lesions. Thieme Revinter Publicações Ltda. 2021-06 2020-09-25 /pmc/articles/PMC8249057/ /pubmed/34239198 http://dx.doi.org/10.1055/s-0040-1712493 Text en Sociedade Brasileira de Ortopedia e Traumatologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Miyahira, Mateus Kenji Christo
Novaretti, João Victor
Astur, Diego Costa
Kaleka, Camila Cohen
Amaro, Joicemar Tarouco
Cohen, Moisés
Larger Chondral Lesions Treated with Collagen Membrane – Matrix-Induced Autologous Chondrogenesis – Show Larger Increase in Clinical Scores
title Larger Chondral Lesions Treated with Collagen Membrane – Matrix-Induced Autologous Chondrogenesis – Show Larger Increase in Clinical Scores
title_full Larger Chondral Lesions Treated with Collagen Membrane – Matrix-Induced Autologous Chondrogenesis – Show Larger Increase in Clinical Scores
title_fullStr Larger Chondral Lesions Treated with Collagen Membrane – Matrix-Induced Autologous Chondrogenesis – Show Larger Increase in Clinical Scores
title_full_unstemmed Larger Chondral Lesions Treated with Collagen Membrane – Matrix-Induced Autologous Chondrogenesis – Show Larger Increase in Clinical Scores
title_short Larger Chondral Lesions Treated with Collagen Membrane – Matrix-Induced Autologous Chondrogenesis – Show Larger Increase in Clinical Scores
title_sort larger chondral lesions treated with collagen membrane – matrix-induced autologous chondrogenesis – show larger increase in clinical scores
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249057/
https://www.ncbi.nlm.nih.gov/pubmed/34239198
http://dx.doi.org/10.1055/s-0040-1712493
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