The Combination Treatment of Curcumin and Probucol Protects Chondrocytes from TNF-α Induced Inflammation by Enhancing Autophagy and Reducing Apoptosis via the PI3K-Akt-mTOR Pathway

Osteoarthritis (OA) is a chronic joint disease characterized by cholesterol accumulation in chondrocytes, cartilage degeneration, as well as extracellular matrix (ECM) destruction, and joint dysfunction. Curcumin, a chemical that can reduce cholesterol levels in OA patients, also can inhibit the pro...

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Detalles Bibliográficos
Autores principales: Han, Guangtao, Zhang, Yubiao, Li, Haohuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249126/
https://www.ncbi.nlm.nih.gov/pubmed/34257809
http://dx.doi.org/10.1155/2021/5558066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249126/
https://www.ncbi.nlm.nih.gov/pubmed/34257809
http://dx.doi.org/10.1155/2021/5558066

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