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Functionally distinct POMC-expressing neuron subpopulations in hypothalamus revealed by intersectional targeting
Pro-opiomelanocortin (POMC)-expressing neurons in the arcuate nucleus of the hypothalamus represent key regulators of metabolic homeostasis. Electrophysiological and single-cell sequencing experiments have revealed a remarkable degree of heterogeneity of these neurons. However, the exact molecular b...
Autores principales: | Biglari, Nasim, Gaziano, Isabella, Schumacher, Jonas, Radermacher, Jan, Paeger, Lars, Klemm, Paul, Chen, Weiyi, Corneliussen, Svenja, Wunderlich, Claudia M., Sue, Michael, Vollmar, Stefan, Klöckener, Tim, Sotelo-Hitschfeld, Tamara, Abbasloo, Amin, Edenhofer, Frank, Reimann, Frank, Gribble, Fiona M., Fenselau, Henning, Kloppenburg, Peter, Wunderlich, Frank T., Brüning, Jens C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249241/ https://www.ncbi.nlm.nih.gov/pubmed/34002087 http://dx.doi.org/10.1038/s41593-021-00854-0 |
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