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Detecting ALK Rearrangement with RT-PCR: A Reliable Approach Compared with Next-Generation Sequencing in Patients with NSCLC

BACKGROUND: Precise detection of anaplastic lymphoma kinase (ALK) rearrangement guides the application of ALK-targeted tyrosine kinase inhibitors (ALK-TKIs) in patients with non-small-cell lung cancer (NSCLC). Next-generation sequencing (NGS) has been widely used in clinics, but DNA-based NGS used t...

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Detalles Bibliográficos
Autores principales:	Kuang, Yukun, Xu, Peihang, Wang, Jiyu, Zheng, Yifan, Sun, Xue, Li, Zimu, Gan, RunJing, Li, Huixia, Guo, Yubiao, Yao, Fei, Zhu, Changbin, Ke, Zunfu, Tang, Kejing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249291/ https://www.ncbi.nlm.nih.gov/pubmed/34133003 http://dx.doi.org/10.1007/s40291-021-00532-8

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