Leveraging the Fragment Length of Circulating Tumour DNA to Improve Molecular Profiling of Solid Tumour Malignancies with Next-Generation Sequencing: A Pathway to Advanced Non-invasive Diagnostics in Precision Oncology?

Circulating cell-free DNA (ccfDNA) has emerged as a promising diagnostic tool in oncology. Identification of tumour-derived ccfDNA (i.e. circulating tumour DNA [ctDNA]) provides non-invasive access to a malignancy’s molecular landscape to diagnose, inform therapeutic strategies, and monitor treatmen...

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Detalles Bibliográficos
Autor principal: Underhill, Hunter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Current Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249304/
https://www.ncbi.nlm.nih.gov/pubmed/34018157
http://dx.doi.org/10.1007/s40291-021-00534-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249304/
https://www.ncbi.nlm.nih.gov/pubmed/34018157
http://dx.doi.org/10.1007/s40291-021-00534-6

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