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Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease

This study aimed to evaluate the efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease. Twenty-five patients with stage III Kümmell disease who received bone cement-augmented pedicle screw fixation at the First Affiliated Hospital of Guangzhou University o...

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Autores principales: Mo, Guo-ye, Zhou, Teng-peng, Guo, Hui-zhi, Li, Yong-xian, Tang, Yong-chao, Guo, Dan-qing, Luo, Pei-jie, Li, Dong-xiao, Yuan, Kai, Mo, Ling, Zhang, Shun-cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249396/
https://www.ncbi.nlm.nih.gov/pubmed/34211025
http://dx.doi.org/10.1038/s41598-021-93013-1
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author Mo, Guo-ye
Zhou, Teng-peng
Guo, Hui-zhi
Li, Yong-xian
Tang, Yong-chao
Guo, Dan-qing
Luo, Pei-jie
Li, Dong-xiao
Yuan, Kai
Mo, Ling
Zhang, Shun-cong
author_facet Mo, Guo-ye
Zhou, Teng-peng
Guo, Hui-zhi
Li, Yong-xian
Tang, Yong-chao
Guo, Dan-qing
Luo, Pei-jie
Li, Dong-xiao
Yuan, Kai
Mo, Ling
Zhang, Shun-cong
author_sort Mo, Guo-ye
collection PubMed
description This study aimed to evaluate the efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease. Twenty-five patients with stage III Kümmell disease who received bone cement-augmented pedicle screw fixation at the First Affiliated Hospital of Guangzhou University of Chinese Medicine between June 2009 and December 2015 were enrolled. All patients were females with a history of osteoporosis. The vertebral Cobb angle (V-Cobb angle), the fixed segment Cobb Angle (S-Cobb angle), pelvic parameters, visual Analogue Scale (VAS) score, and Oswestry Disability Index (ODI) were assessed preoperatively, postoperatively and at the final follow-up. Complications, loosening rate, operation time, and intraoperative bleeding were recorded. The average lumbar vertebral density T-value was − 3.68 ± 0.71 SD, and the average age was 71.84 ± 5.39. The V-Cobb angle, S-Cobb angle, and Sagittal Vertical Axis (SVA) were significantly smaller postoperatively compared to the preoperative values. The VAS and ODI at 1 month after surgery were 3.60 ± 1.00 and 36.04 ± 6.12%, respectively, which were both significantly lower than before surgery (VAS: 8.56 ± 1.04, ODI: 77.80 ± 6.57%). Bone cement-augmented pedicle screw fixation is a safe and effective treatment for stage III Kümmell disease. It can effectively correct kyphosis, restore and maintain sagittal balance, and maintain spinal stability.
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spelling pubmed-82493962021-07-06 Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease Mo, Guo-ye Zhou, Teng-peng Guo, Hui-zhi Li, Yong-xian Tang, Yong-chao Guo, Dan-qing Luo, Pei-jie Li, Dong-xiao Yuan, Kai Mo, Ling Zhang, Shun-cong Sci Rep Article This study aimed to evaluate the efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease. Twenty-five patients with stage III Kümmell disease who received bone cement-augmented pedicle screw fixation at the First Affiliated Hospital of Guangzhou University of Chinese Medicine between June 2009 and December 2015 were enrolled. All patients were females with a history of osteoporosis. The vertebral Cobb angle (V-Cobb angle), the fixed segment Cobb Angle (S-Cobb angle), pelvic parameters, visual Analogue Scale (VAS) score, and Oswestry Disability Index (ODI) were assessed preoperatively, postoperatively and at the final follow-up. Complications, loosening rate, operation time, and intraoperative bleeding were recorded. The average lumbar vertebral density T-value was − 3.68 ± 0.71 SD, and the average age was 71.84 ± 5.39. The V-Cobb angle, S-Cobb angle, and Sagittal Vertical Axis (SVA) were significantly smaller postoperatively compared to the preoperative values. The VAS and ODI at 1 month after surgery were 3.60 ± 1.00 and 36.04 ± 6.12%, respectively, which were both significantly lower than before surgery (VAS: 8.56 ± 1.04, ODI: 77.80 ± 6.57%). Bone cement-augmented pedicle screw fixation is a safe and effective treatment for stage III Kümmell disease. It can effectively correct kyphosis, restore and maintain sagittal balance, and maintain spinal stability. Nature Publishing Group UK 2021-07-01 /pmc/articles/PMC8249396/ /pubmed/34211025 http://dx.doi.org/10.1038/s41598-021-93013-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Mo, Guo-ye
Zhou, Teng-peng
Guo, Hui-zhi
Li, Yong-xian
Tang, Yong-chao
Guo, Dan-qing
Luo, Pei-jie
Li, Dong-xiao
Yuan, Kai
Mo, Ling
Zhang, Shun-cong
Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease
title Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease
title_full Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease
title_fullStr Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease
title_full_unstemmed Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease
title_short Long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage III Kümmell disease
title_sort long-term efficacy and safety of bone cement-augmented pedicle screw fixation for stage iii kümmell disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249396/
https://www.ncbi.nlm.nih.gov/pubmed/34211025
http://dx.doi.org/10.1038/s41598-021-93013-1
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