A susceptibility locus in the IL12B but not LILRA3 region is associated with vascular damage in Takayasu arteritis

HLA-B*52 is an established genetic factor in Takayasu arteritis (TAK). Recently, single nucleotide polymorphisms (SNPs) in IL12B (rs6871626) and LILRA3 (rs103294) were newly identified as non-HLA susceptibility loci in TAK. Here, we examined how these SNPs contribute to clinical characteristics and...

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Detalles Bibliográficos
Autores principales: Kadoba, Keiichiro, Watanabe, Ryu, Iwasaki, Takeshi, Nakajima, Toshiki, Kitagori, Koji, Akizuki, Shuji, Murakami, Kosaku, Nakashima, Ran, Hashimoto, Motomu, Tanaka, Masao, Ohmura, Koichiro, Morinobu, Akio, Terao, Chikashi, Yoshifuji, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249518/
https://www.ncbi.nlm.nih.gov/pubmed/34211061
http://dx.doi.org/10.1038/s41598-021-93213-9

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