Multi-country evaluation of RISK6, a 6-gene blood transcriptomic signature, for tuberculosis diagnosis and treatment monitoring

There is a crucial need for non-sputum-based TB tests. Here, we evaluate the performance of RISK6, a human-blood transcriptomic signature, for TB screening, triage and treatment monitoring. RISK6 performance was also compared to that of two IGRAs: one based on RD1 antigens (QuantiFERON-TB Gold Plus,...

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Detalles Bibliográficos
Autores principales: Bayaa, Rim, Ndiaye, Mame Diarra Bousso, Chedid, Carole, Kokhreidze, Eka, Tukvadze, Nestani, Banu, Sayera, Uddin, Mohammad Khaja Mafij, Biswas, Samanta, Nasrin, Rumana, Ranaivomanana, Paulo, Raherinandrasana, Antso Hasina, Rakotonirina, Julio, Rasolofo, Voahangy, Delogu, Giovanni, De Maio, Flavio, Goletti, Delia, Endtz, Hubert, Ader, Florence, Hamze, Monzer, Ismail, Mohamad Bachar, Pouzol, Stéphane, Rakotosamimanana, Niaina, Hoffmann, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249600/
https://www.ncbi.nlm.nih.gov/pubmed/34211042
http://dx.doi.org/10.1038/s41598-021-93059-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249600/
https://www.ncbi.nlm.nih.gov/pubmed/34211042
http://dx.doi.org/10.1038/s41598-021-93059-1

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