Cartilage oligomeric matrix protein is an endogenous β-arrestin-2-selective allosteric modulator of AT1 receptor counteracting vascular injury

Compelling evidence has revealed that biased activation of G protein-coupled receptor (GPCR) signaling, including angiotensin II (AngII) receptor type 1 (AT1) signaling, plays pivotal roles in vascular homeostasis and injury, but whether a clinically relevant endogenous biased antagonism of AT1 sign...

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Detalles Bibliográficos
Autores principales: Fu, Yi, Huang, Yaqian, Yang, Zhao, Chen, Yufei, Zheng, Jingang, Mao, Chenfeng, Li, Zhiqing, Liu, Zhixin, Yu, Bing, Li, Tuoyi, Wang, Meili, Xu, Chanjuan, Zhou, Yiwei, Zhao, Guizhen, Jia, Yiting, Guo, Wei, Jia, Xin, Zhang, Tao, Li, Li, Liu, Ziyi, Guo, Shengchao, Ma, Mingliang, Zhang, Heng, Liu, Bo, Du, Junbao, Wang, Wengong, Tang, Chaoshu, Gao, Pei, Xu, Qingbo, Wang, Xian, Liu, Jianfeng, Sun, Jinpeng, Kong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249609/
https://www.ncbi.nlm.nih.gov/pubmed/33510386
http://dx.doi.org/10.1038/s41422-020-00464-8

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