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Structural basis of the activation of c-MET receptor

The c-MET receptor is a receptor tyrosine kinase (RTK) that plays essential roles in normal cell development and motility. Aberrant activation of c-MET can lead to both tumors growth and metastatic progression of cancer cells. C-MET can be activated by either hepatocyte growth factor (HGF), or its n...

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Detalles Bibliográficos
Autores principales:	Uchikawa, Emiko, Chen, Zhiming, Xiao, Guan-Yu, Zhang, Xuewu, Bai, Xiao-chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249616/ https://www.ncbi.nlm.nih.gov/pubmed/34210960 http://dx.doi.org/10.1038/s41467-021-24367-3

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