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Dissecting human embryonic skeletal stem cell ontogeny by single-cell transcriptomic and functional analyses

Human skeletal stem cells (SSCs) have been discovered in fetal and adult long bones. However, the spatiotemporal ontogeny of human embryonic SSCs during early skeletogenesis remains elusive. Here we map the transcriptional landscape of human limb buds and embryonic long bones at single-cell resoluti...

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Detalles Bibliográficos
Autores principales: He, Jian, Yan, Jing, Wang, Jianfang, Zhao, Liangyu, Xin, Qian, Zeng, Yang, Sun, Yuxi, Zhang, Han, Bai, Zhijie, Li, Zongcheng, Ni, Yanli, Gong, Yandong, Li, Yunqiao, He, Han, Bian, Zhilei, Lan, Yu, Ma, Chunyu, Bian, Lihong, Zhu, Heng, Liu, Bing, Yue, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249634/
https://www.ncbi.nlm.nih.gov/pubmed/33473154
http://dx.doi.org/10.1038/s41422-021-00467-z