Empowering clinical research in a decentralized world

The COVID-19 pandemic has been a catalyst for the implementation of decentralized clinical trials (DCTs) enabled by digital health technologies (DHTs) in the field while curtailing in-person interactions and putting significant demands on health care resources. DHTs offer improvements in real-time d...

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Autores principales: De Brouwer, Walter, Patel, Chirag J., Manrai, Arjun K., Rodriguez-Chavez, Isaac R., Shah, Nirav R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249659/
https://www.ncbi.nlm.nih.gov/pubmed/34211085
http://dx.doi.org/10.1038/s41746-021-00473-w
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author De Brouwer, Walter
Patel, Chirag J.
Manrai, Arjun K.
Rodriguez-Chavez, Isaac R.
Shah, Nirav R.
author_facet De Brouwer, Walter
Patel, Chirag J.
Manrai, Arjun K.
Rodriguez-Chavez, Isaac R.
Shah, Nirav R.
author_sort De Brouwer, Walter
collection PubMed
description The COVID-19 pandemic has been a catalyst for the implementation of decentralized clinical trials (DCTs) enabled by digital health technologies (DHTs) in the field while curtailing in-person interactions and putting significant demands on health care resources. DHTs offer improvements in real-time data acquisition remotely while maintaining privacy and security. Here, we describe the implications of technologies, including edge computing, zero-trust environments, and federated computing in DCTs enabled by DHTs. Taken together, these technologies—in the setting of policy and regulation that enable their use while protecting the users—extend the scope and accelerate the pace of clinical research.
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spelling pubmed-82496592021-07-20 Empowering clinical research in a decentralized world De Brouwer, Walter Patel, Chirag J. Manrai, Arjun K. Rodriguez-Chavez, Isaac R. Shah, Nirav R. NPJ Digit Med Comment The COVID-19 pandemic has been a catalyst for the implementation of decentralized clinical trials (DCTs) enabled by digital health technologies (DHTs) in the field while curtailing in-person interactions and putting significant demands on health care resources. DHTs offer improvements in real-time data acquisition remotely while maintaining privacy and security. Here, we describe the implications of technologies, including edge computing, zero-trust environments, and federated computing in DCTs enabled by DHTs. Taken together, these technologies—in the setting of policy and regulation that enable their use while protecting the users—extend the scope and accelerate the pace of clinical research. Nature Publishing Group UK 2021-07-01 /pmc/articles/PMC8249659/ /pubmed/34211085 http://dx.doi.org/10.1038/s41746-021-00473-w Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Comment
De Brouwer, Walter
Patel, Chirag J.
Manrai, Arjun K.
Rodriguez-Chavez, Isaac R.
Shah, Nirav R.
Empowering clinical research in a decentralized world
title Empowering clinical research in a decentralized world
title_full Empowering clinical research in a decentralized world
title_fullStr Empowering clinical research in a decentralized world
title_full_unstemmed Empowering clinical research in a decentralized world
title_short Empowering clinical research in a decentralized world
title_sort empowering clinical research in a decentralized world
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249659/
https://www.ncbi.nlm.nih.gov/pubmed/34211085
http://dx.doi.org/10.1038/s41746-021-00473-w
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