A region within the third extracellular loop of rat Aquaporin 6 precludes trafficking to plasma membrane in a heterologous cell line

The inability to over-express Aquaporin 6 (AQP6) in the plasma membrane of heterologous cells has hampered efforts to further characterize the function of this aquaglyceroporin membrane protein at atomic detail using crystallographic approaches. Using an Aquaporin 3-tGFP Reporter (AGR) system we hav...

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Detalles Bibliográficos
Autores principales: Soler, D. C., Kowatz, T., Sloan, A. E., McCormick, T. S., Cooper, K. D., Stepanyan, R., Engel, A., Vahedi-Faridi, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249660/
https://www.ncbi.nlm.nih.gov/pubmed/34211055
http://dx.doi.org/10.1038/s41598-021-93117-8

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