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Local application of Usag-1 siRNA can promote tooth regeneration in Runx2-deficient mice

Runt-related transcription factor 2 (Runx2)-deficient mice can be used to model congenital tooth agenesis in humans. Conversely, uterine sensitization-associated gene-1 (Usag-1)-deficient mice exhibit supernumerary tooth formation. Arrested tooth formation can be restored by crossing both knockout-m...

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Detalles Bibliográficos
Autores principales:	Mishima, Sayaka, Takahashi, Katsu, Kiso, Honoka, Murashima-Suginami, Akiko, Tokita, Yoshihito, Jo, Jun-Ichiro, Uozumi, Ryuji, Nambu, Yukiko, Huang, Boyen, Harada, Hidemitsu, Komori, Toshihisa, Sugai, Manabu, Tabata, Yasuhiko, Bessho, Kazuhisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249669/ https://www.ncbi.nlm.nih.gov/pubmed/34211084 http://dx.doi.org/10.1038/s41598-021-93256-y

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