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SARS-COV-2 spike binding to ACE2 in living cells monitored by TR-FRET
Targeting the interaction between the SARS-CoV-2 spike protein and human ACE2, its primary cell membrane receptor, is a promising therapeutic strategy to prevent viral entry. Recent in vitro studies revealed that the receptor binding domain (RBD) of the spike protein plays a prominent role in ACE2 b...
Autores principales: | Cecon, Erika, Burridge, Matilda, Cao, Longxing, Carter, Lauren, Ravichandran, Rashmi, Dam, Julie, Jockers, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249686/ https://www.ncbi.nlm.nih.gov/pubmed/34246414 http://dx.doi.org/10.1016/j.chembiol.2021.06.008 |
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