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A follow-up study of patients with COVID-19 presenting with seizures
OBJECTIVE: We performed a follow-up study of patients with COVID-19 presenting with seizures. METHODS: All consecutive patients with seizures, who were referred to Namazee Hospital, Shiraz, Iran, with a diagnosis of COVID-19, from 10 August 2020 until 20 October 2020 were included in this longitudin...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249711/ https://www.ncbi.nlm.nih.gov/pubmed/34273743 http://dx.doi.org/10.1016/j.yebeh.2021.108207 |
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author | Asadi-Pooya, Ali A. Kouhanjani, Mohsen Farjoud Nemati, Hamid Emami, Amir Javanmardi, Fatemeh |
author_facet | Asadi-Pooya, Ali A. Kouhanjani, Mohsen Farjoud Nemati, Hamid Emami, Amir Javanmardi, Fatemeh |
author_sort | Asadi-Pooya, Ali A. |
collection | PubMed |
description | OBJECTIVE: We performed a follow-up study of patients with COVID-19 presenting with seizures. METHODS: All consecutive patients with seizures, who were referred to Namazee Hospital, Shiraz, Iran, with a diagnosis of COVID-19, from 10 August 2020 until 20 October 2020 were included in this longitudinal study. The clinical data were collected by the admitting physician. In a follow-up phone call to the discharged patients (after eight weeks or more), we inquired their seizure outcome. RESULTS: In total, 32 patients were studied; 28 patients were followed. Twelve patients (37.5%) presented with a single tonic-clonic seizure and nine (28.1%) had convulsive status epilepticus; one patient had functional (psychogenic) seizures. Ten patients (31.3%) had pre-existing epilepsy, eight others (25%) had pre-existing CNS problems (without epilepsy), one person (3.1%) had pre-existing functional seizures, and 13 individuals (40.1%) neither had epilepsy nor had other CNS problems. Eight patients (28.6%) reported experiencing seizure(s) after being discharged from the hospital; six of these had pre-existing epilepsy and one had pre-existing functional seizures. One patient, who had a newly developed ischemic brain infarction, reported experiencing recurrent seizures. CONCLUSION: Seizures in patients with COVID-19 are either acute symptomatic (in about two-thirds) or an exacerbation of a pre-existing epilepsy/functional seizures (in about one-third). A thorough investigation of the underlying etiology of seizures in patients with COVID-19 is necessary. Seizure outcome in patients, who are hospitalized with COVID-19 and seizures, is generally good. |
format | Online Article Text |
id | pubmed-8249711 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-82497112021-07-02 A follow-up study of patients with COVID-19 presenting with seizures Asadi-Pooya, Ali A. Kouhanjani, Mohsen Farjoud Nemati, Hamid Emami, Amir Javanmardi, Fatemeh Epilepsy Behav Article OBJECTIVE: We performed a follow-up study of patients with COVID-19 presenting with seizures. METHODS: All consecutive patients with seizures, who were referred to Namazee Hospital, Shiraz, Iran, with a diagnosis of COVID-19, from 10 August 2020 until 20 October 2020 were included in this longitudinal study. The clinical data were collected by the admitting physician. In a follow-up phone call to the discharged patients (after eight weeks or more), we inquired their seizure outcome. RESULTS: In total, 32 patients were studied; 28 patients were followed. Twelve patients (37.5%) presented with a single tonic-clonic seizure and nine (28.1%) had convulsive status epilepticus; one patient had functional (psychogenic) seizures. Ten patients (31.3%) had pre-existing epilepsy, eight others (25%) had pre-existing CNS problems (without epilepsy), one person (3.1%) had pre-existing functional seizures, and 13 individuals (40.1%) neither had epilepsy nor had other CNS problems. Eight patients (28.6%) reported experiencing seizure(s) after being discharged from the hospital; six of these had pre-existing epilepsy and one had pre-existing functional seizures. One patient, who had a newly developed ischemic brain infarction, reported experiencing recurrent seizures. CONCLUSION: Seizures in patients with COVID-19 are either acute symptomatic (in about two-thirds) or an exacerbation of a pre-existing epilepsy/functional seizures (in about one-third). A thorough investigation of the underlying etiology of seizures in patients with COVID-19 is necessary. Seizure outcome in patients, who are hospitalized with COVID-19 and seizures, is generally good. Elsevier Inc. 2021-09 2021-07-02 /pmc/articles/PMC8249711/ /pubmed/34273743 http://dx.doi.org/10.1016/j.yebeh.2021.108207 Text en © 2021 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Asadi-Pooya, Ali A. Kouhanjani, Mohsen Farjoud Nemati, Hamid Emami, Amir Javanmardi, Fatemeh A follow-up study of patients with COVID-19 presenting with seizures |
title | A follow-up study of patients with COVID-19 presenting with seizures |
title_full | A follow-up study of patients with COVID-19 presenting with seizures |
title_fullStr | A follow-up study of patients with COVID-19 presenting with seizures |
title_full_unstemmed | A follow-up study of patients with COVID-19 presenting with seizures |
title_short | A follow-up study of patients with COVID-19 presenting with seizures |
title_sort | follow-up study of patients with covid-19 presenting with seizures |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249711/ https://www.ncbi.nlm.nih.gov/pubmed/34273743 http://dx.doi.org/10.1016/j.yebeh.2021.108207 |
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