Genome stabilization by RAD51‐stimulatory compound 1 enhances efficiency of somatic cell nuclear transfer‐mediated reprogramming and full‐term development of cloned mouse embryos

OBJECTIVES: The genetic instability and DNA damage arise during transcription factor‐mediated reprogramming of somatic cells, and its efficiency may be reduced due to abnormal chromatin remodelling. The efficiency in somatic cell nuclear transfer (SCNT)‐mediated reprogramming is also very low, and i...

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Detalles Bibliográficos
Autores principales: Lee, Ah Reum, Park, Ji‐Hoon, Shim, Sung Han, Hong, Kwonho, La, Hyeonwoo, Park, Kyung‐Soon, Lee, Dong Ryul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249786/
https://www.ncbi.nlm.nih.gov/pubmed/34021643
http://dx.doi.org/10.1111/cpr.13059

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