EZH2‐mediated inhibition of KLF14 expression promotes HSCs activation and liver fibrosis by downregulating PPARγ

OBJECTIVES: Induction of deactivation and apoptosis of hepatic stellate cells (HSCs) are principal therapeutic strategies for liver fibrosis. Krüppel‐like factor 14 (KLF14) regulates various biological processes, however, roles, mechanisms and implications of KLF14 in liver fibrosis are unknown. MAT...

Descripción completa

Detalles Bibliográficos
Autores principales: Du, Zhipeng, Liu, Mei, Wang, Zhihui, Lin, Zhuoying, Feng, Yangyang, Tian, Dean, Xia, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249795/
https://www.ncbi.nlm.nih.gov/pubmed/34031939
http://dx.doi.org/10.1111/cpr.13072

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249795/
https://www.ncbi.nlm.nih.gov/pubmed/34031939
http://dx.doi.org/10.1111/cpr.13072

Ejemplares similares