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Exocrine pancreas proteases regulate β-cell proliferation in zebrafish ciliopathy models and in murine systems
Pancreatic β-cells are a critical cell type in the pathology of diabetes. Models of genetic syndromes featuring diabetes can provide novel mechanistic insights into regulation of β-cells in the context of disease. We previously examined β-cell mass in models of two ciliopathies, Alström Syndrome (AS...
Autores principales: | Hostelley, Timothy L., Nesmith, Jessica E., Larkin, Emily, Jones, Amanda, Boyes, Daniel, Leitch, Carmen C., Fontaine, Magali, Zaghloul, Norann A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249909/ https://www.ncbi.nlm.nih.gov/pubmed/34125181 http://dx.doi.org/10.1242/bio.046839 |
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