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Chronic Immune Activation and CD4(+) T Cell Lymphopenia in Healthy African Individuals: Perspectives for SARS-CoV-2 Vaccine Efficacy
Chronic immune activation has been considered as the driving force for CD4(+) T cell depletion in people infected with HIV-1. Interestingly, the normal immune profile of adult HIV-negative individuals living in Africa also exhibit chronic immune activation, reminiscent of that observed in HIV-1 infe...
Autores principales: | Wolday, Dawit, Ndungu, Francis M., Gómez-Pérez, Gloria P., de Wit, Tobias F. Rinke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8249933/ https://www.ncbi.nlm.nih.gov/pubmed/34220854 http://dx.doi.org/10.3389/fimmu.2021.693269 |
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