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Phosphoinositide 3-Kinase p110 Delta Differentially Restrains and Directs Naïve Versus Effector CD8(+) T Cell Transcriptional Programs

Phosphoinositide 3-kinase p110 delta (PI3K p110δ) is pivotal for CD8(+) T cell immune responses. The current study explores PI3K p110δ induction and repression of antigen receptor and cytokine regulated programs to inform how PI3K p110δ directs CD8(+) T cell fate. The studies force a revision of the...

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Detalles Bibliográficos
Autores principales:	Spinelli, Laura, Marchingo, Julia M., Nomura, Aneela, Damasio, Marcos P., Cantrell, Doreen A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8250422/ https://www.ncbi.nlm.nih.gov/pubmed/34220851 http://dx.doi.org/10.3389/fimmu.2021.691997

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