U shape association of hemoglobin level with in-hospital mortality for COVID-19 patients

Our hypothesis was that high hemoglobin (Hb) level might be associated with hypercoagulable state and death due to COVID-19. Of the 9467 hospitalized COVID-19 patients, patients were subdivided into 5 groups based on the level of Hb; Hb < 10 g/dL, 10 g/dL ≤ Hb < 12 g/dL, 12 g/dL ≤ Hb < 14 g...

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Autores principales: Kuno, Toshiki, So, Matsuo, Takahashi, Mai, Egorova, Natalia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8250547/
https://www.ncbi.nlm.nih.gov/pubmed/34213716
http://dx.doi.org/10.1007/s11239-021-02516-1
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author Kuno, Toshiki
So, Matsuo
Takahashi, Mai
Egorova, Natalia N.
author_facet Kuno, Toshiki
So, Matsuo
Takahashi, Mai
Egorova, Natalia N.
author_sort Kuno, Toshiki
collection PubMed
description Our hypothesis was that high hemoglobin (Hb) level might be associated with hypercoagulable state and death due to COVID-19. Of the 9467 hospitalized COVID-19 patients, patients were subdivided into 5 groups based on the level of Hb; Hb < 10 g/dL, 10 g/dL ≤ Hb < 12 g/dL, 12 g/dL ≤ Hb < 14 g/dL, 14 g/dL ≤ Hb < 16 g/dL, and Hb ≥ 16 g/dL. Compared to patients with 12 g/dL ≤ Hb < 14 g/dL, patients with Hb ≥ 16 g/dL had significantly higher adjusted in-hospital mortality (OR [95% CI] 1.62 [1.15–2.27], P = 0.005). SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11239-021-02516-1.
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spelling pubmed-82505472021-07-02 U shape association of hemoglobin level with in-hospital mortality for COVID-19 patients Kuno, Toshiki So, Matsuo Takahashi, Mai Egorova, Natalia N. J Thromb Thrombolysis Article Our hypothesis was that high hemoglobin (Hb) level might be associated with hypercoagulable state and death due to COVID-19. Of the 9467 hospitalized COVID-19 patients, patients were subdivided into 5 groups based on the level of Hb; Hb < 10 g/dL, 10 g/dL ≤ Hb < 12 g/dL, 12 g/dL ≤ Hb < 14 g/dL, 14 g/dL ≤ Hb < 16 g/dL, and Hb ≥ 16 g/dL. Compared to patients with 12 g/dL ≤ Hb < 14 g/dL, patients with Hb ≥ 16 g/dL had significantly higher adjusted in-hospital mortality (OR [95% CI] 1.62 [1.15–2.27], P = 0.005). SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s11239-021-02516-1. Springer US 2021-07-02 2022 /pmc/articles/PMC8250547/ /pubmed/34213716 http://dx.doi.org/10.1007/s11239-021-02516-1 Text en © The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Kuno, Toshiki
So, Matsuo
Takahashi, Mai
Egorova, Natalia N.
U shape association of hemoglobin level with in-hospital mortality for COVID-19 patients
title U shape association of hemoglobin level with in-hospital mortality for COVID-19 patients
title_full U shape association of hemoglobin level with in-hospital mortality for COVID-19 patients
title_fullStr U shape association of hemoglobin level with in-hospital mortality for COVID-19 patients
title_full_unstemmed U shape association of hemoglobin level with in-hospital mortality for COVID-19 patients
title_short U shape association of hemoglobin level with in-hospital mortality for COVID-19 patients
title_sort u shape association of hemoglobin level with in-hospital mortality for covid-19 patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8250547/
https://www.ncbi.nlm.nih.gov/pubmed/34213716
http://dx.doi.org/10.1007/s11239-021-02516-1
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