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Identification of mutation resistance coldspots for targeting the SARS‐CoV2 main protease
Mutations in the novel coronavirus SARS‐CoV2 are the major concern as they might lead to drug/vaccine resistance. In the host cell, the virus largely depends on the main protease (M(pro)) to regulate infection hence it is one of the most attractive targets for inhibitor design. However, >19,000 m...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8250577/ https://www.ncbi.nlm.nih.gov/pubmed/33749986 http://dx.doi.org/10.1002/iub.2465 |