Nuclear IGF1R interacts with NuMA and regulates 53BP1-dependent DNA double-strand break repair in colorectal cancer

Nuclear insulin-like growth factor 1 receptor (nIGF1R) has been associated with poor overall survival and chemotherapy resistance in various types of cancer; however, the underlying mechanism remains unclear. In the present study, immunoprecipitation-coupled mass spectrometry was performed in an IGF...

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Detalles Bibliográficos
Autores principales: Yang, Chen, Zhang, Yifan, Segar, Nelly, Huang, Changhao, Zeng, Pengwei, Tan, Xiangzhou, Mao, Linfeng, Chen, Zhikang, Haglund, Felix, Larsson, Olle, Chen, Zihua, Lin, Yingbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8250583/
https://www.ncbi.nlm.nih.gov/pubmed/34165167
http://dx.doi.org/10.3892/or.2021.8119

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