Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin

We describe a case of a patient with atrial fibrillation, anticoagulated with dabigatran, that developed severe knee skin necrosis in the setting of an acute periprosthetic knee infection, after initiating low-molecular-weight heparin. A wide range of etiology hypotheses was discussed within a multi...

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Autores principales: Fonte, Hélder, Carvalho, André, Rosa, João, Pereira, Cláudia, Pereira, Alexandre, Sousa, Ricardo, further members of the Porto Bone and Joint Infection Unit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Copernicus GmbH 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251103/
https://www.ncbi.nlm.nih.gov/pubmed/34235047
http://dx.doi.org/10.5194/jbji-6-235-2021
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author Fonte, Hélder
Carvalho, André
Rosa, João
Pereira, Cláudia
Pereira, Alexandre
Sousa, Ricardo
further members of the Porto Bone and Joint Infection Unit,
author_facet Fonte, Hélder
Carvalho, André
Rosa, João
Pereira, Cláudia
Pereira, Alexandre
Sousa, Ricardo
further members of the Porto Bone and Joint Infection Unit,
author_sort Fonte, Hélder
collection PubMed
description We describe a case of a patient with atrial fibrillation, anticoagulated with dabigatran, that developed severe knee skin necrosis in the setting of an acute periprosthetic knee infection, after initiating low-molecular-weight heparin. A wide range of etiology hypotheses was discussed within a multidisciplinary team. The complex approach consisted of treating the underlying infection, multiple types of soft-tissue management, and stopping enoxaparin.
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spelling pubmed-82511032021-07-06 Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin Fonte, Hélder Carvalho, André Rosa, João Pereira, Cláudia Pereira, Alexandre Sousa, Ricardo further members of the Porto Bone and Joint Infection Unit, J Bone Jt Infect Case Report We describe a case of a patient with atrial fibrillation, anticoagulated with dabigatran, that developed severe knee skin necrosis in the setting of an acute periprosthetic knee infection, after initiating low-molecular-weight heparin. A wide range of etiology hypotheses was discussed within a multidisciplinary team. The complex approach consisted of treating the underlying infection, multiple types of soft-tissue management, and stopping enoxaparin. Copernicus GmbH 2021-06-28 /pmc/articles/PMC8251103/ /pubmed/34235047 http://dx.doi.org/10.5194/jbji-6-235-2021 Text en Copyright: © 2021 Hélder Fonte et al. https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/
spellingShingle Case Report
Fonte, Hélder
Carvalho, André
Rosa, João
Pereira, Cláudia
Pereira, Alexandre
Sousa, Ricardo
further members of the Porto Bone and Joint Infection Unit,
Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin
title Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin
title_full Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin
title_fullStr Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin
title_full_unstemmed Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin
title_short Extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin
title_sort extensive skin necrosis after periprosthetic knee infection: a case that highlights the possibility of complications induced by low-molecular-weight heparin
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251103/
https://www.ncbi.nlm.nih.gov/pubmed/34235047
http://dx.doi.org/10.5194/jbji-6-235-2021
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