Introduction to molecular replacement: a time perspective

This article provides an introduction to the crystal phasing technique known as molecular replacement. The available software is reviewed, and the prospects for future developments are considered. Several examples are described in detail to illustrate potential problems. A brief account of past prog...

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Detalles Bibliográficos
Autor principal: Dodson, Eleanor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Topical Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251348/
https://www.ncbi.nlm.nih.gov/pubmed/34196614
http://dx.doi.org/10.1107/S2059798321004368
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author Dodson, Eleanor
author_facet Dodson, Eleanor
author_sort Dodson, Eleanor
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description This article provides an introduction to the crystal phasing technique known as molecular replacement. The available software is reviewed, and the prospects for future developments are considered. Several examples are described in detail to illustrate potential problems. A brief account of past progress is included. The basic crystallographic equations underlying the procedures are given in an appendix.
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spelling pubmed-82513482021-07-12 Introduction to molecular replacement: a time perspective Dodson, Eleanor Acta Crystallogr D Struct Biol Topical Reviews This article provides an introduction to the crystal phasing technique known as molecular replacement. The available software is reviewed, and the prospects for future developments are considered. Several examples are described in detail to illustrate potential problems. A brief account of past progress is included. The basic crystallographic equations underlying the procedures are given in an appendix. International Union of Crystallography 2021-06-18 /pmc/articles/PMC8251348/ /pubmed/34196614 http://dx.doi.org/10.1107/S2059798321004368 Text en © Dodson 2021 https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Topical Reviews
Dodson, Eleanor
Introduction to molecular replacement: a time perspective
title Introduction to molecular replacement: a time perspective
title_full Introduction to molecular replacement: a time perspective
title_fullStr Introduction to molecular replacement: a time perspective
title_full_unstemmed Introduction to molecular replacement: a time perspective
title_short Introduction to molecular replacement: a time perspective
title_sort introduction to molecular replacement: a time perspective
topic Topical Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251348/
https://www.ncbi.nlm.nih.gov/pubmed/34196614
http://dx.doi.org/10.1107/S2059798321004368
work_keys_str_mv AT dodsoneleanor introductiontomolecularreplacementatimeperspective

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