Human type 1 and type 2 conventional dendritic cells express indoleamine 2,3‐dioxygenase 1 with functional effects on T cell priming

Dendritic cells (DCs) are key regulators of the immune system that shape T cell responses. Regulation of T cell induction by DCs may occur via the intracellular enzyme indoleamine 2,3‐dioxygenase 1 (IDO), which catalyzes conversion of the essential amino acid tryptophan into kynurenine. Here, we exa...

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Detalles Bibliográficos
Autores principales: Sittig, Simone P., van Beek, Jasper J. P., Flórez‐Grau, Georgina, Weiden, Jorieke, Buschow, Sonja I., van der Net, Mirjam C., van Slooten, Rianne, Verbeek, Marcel M., Geurtz, P. Ben H., Textor, Johannes, Figdor, Carl G., de Vries, I. Jolanda M., Schreibelt, Gerty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Immunomodulation and immune therapies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251546/
https://www.ncbi.nlm.nih.gov/pubmed/33675038
http://dx.doi.org/10.1002/eji.202048580

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