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Trifluorinated Tetralins via I(I)/I(III)‐Catalysed Ring Expansion: Programming Conformation by [CH(2)CH(2)] → [CF(2)CHF] Isosterism

Saturated, fluorinated carbocycles are emerging as important modules for contemporary drug discovery. To expand the current portfolio, the synthesis of novel trifluorinated tetralins has been achieved. Fluorinated methyleneindanes serve as convenient precursors and undergo efficient difluorinative r...

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Detalles Bibliográficos
Autores principales:	Neufeld, Jessica, Stünkel, Timo, Mück‐Lichtenfeld, Christian, Daniliuc, Constantin G., Gilmour, Ryan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251640/ https://www.ncbi.nlm.nih.gov/pubmed/33721384 http://dx.doi.org/10.1002/anie.202102222

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