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A Cytotoxic Bis(1,2,3‐triazol‐5‐ylidene)carbazolide Gold(III) Complex Targets DNA by Partial Intercalation

The syntheses of bis(triazolium)carbazole precursors and their corresponding coinage metal (Au, Ag) complexes are reported. For alkylated triazolium salts, di‐ or tetranuclear complexes with bridging ligands were isolated, while the bis(aryl) analogue afforded a bis(carbene) Au(I)‐CNC pincer complex...

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Detalles Bibliográficos
Autores principales: van der Westhuizen, Danielle, Slabber, Cathryn A., Fernandes, Manuel A., Joubert, Daniël F., Kleinhans, George, van der Westhuizen, C. Johan, Stander, André, Munro, Orde Q., Bezuidenhout, Daniela I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251726/
https://www.ncbi.nlm.nih.gov/pubmed/33822431
http://dx.doi.org/10.1002/chem.202100598

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