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Periprostatic adipose tissue promotes prostate cancer resistance to docetaxel by paracrine IGF‐1 upregulation of TUBB2B beta‐tubulin isoform

Growing evidence supports the pivotal role played by periprostatic adipose tissue (PPAT) in prostate cancer (PCa) microenvironment. We investigated whether PPAT can affect response to Docetaxel (DCTX) and the mechanisms associated. Conditioned medium was collected from the in vitro differentiated ad...

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Detalles Bibliográficos
Autores principales: Liotti, Antonietta, La Civita, Evelina, Cennamo, Michele, Crocetto, Felice, Ferro, Matteo, Guadagno, Elia, Insabato, Luigi, Imbimbo, Ciro, Palmieri, Alessandro, Mirone, Vincenzo, Liguoro, Pasquale, Formisano, Pietro, Beguinot, Francesco, Terracciano, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251776/
https://www.ncbi.nlm.nih.gov/pubmed/33734457
http://dx.doi.org/10.1002/pros.24117