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Single‐Molecule Counting Coupled to Rapid Amplification Enables Detection of α‐Synuclein Aggregates in Cerebrospinal Fluid of Parkinson's Disease Patients
α‐Synuclein aggregation is a hallmark of Parkinson's disease and a promising biomarker for early detection and assessment of disease progression. The prospect of a molecular test for Parkinson's disease is materializing with the recent developments of detection methods based on amplificati...
Autores principales: | Bhumkar, Akshay, Magnan, Chloe, Lau, Derrick, Jun, Eugene Soh Wei, Dzamko, Nicolas, Gambin, Yann, Sierecki, Emma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251908/ https://www.ncbi.nlm.nih.gov/pubmed/33511725 http://dx.doi.org/10.1002/anie.202014898 |
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