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MR‐guided proton therapy: Impact of magnetic fields on the detector response

PURPOSE: To investigate the response of detectors for proton dosimetry in the presence of magnetic fields. MATERIAL AND METHODS: Four ionization chambers (ICs), two thimble‐type and two plane‐parallel‐type, and a diamond detector were investigated. All detectors were irradiated with homogeneous sing...

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Autores principales: Fuchs, Hermann, Padilla‐Cabal, Fatima, Zimmermann, Lukas, Palmans, Hugo, Georg, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251909/
https://www.ncbi.nlm.nih.gov/pubmed/33326614
http://dx.doi.org/10.1002/mp.14660
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author Fuchs, Hermann
Padilla‐Cabal, Fatima
Zimmermann, Lukas
Palmans, Hugo
Georg, Dietmar
author_facet Fuchs, Hermann
Padilla‐Cabal, Fatima
Zimmermann, Lukas
Palmans, Hugo
Georg, Dietmar
author_sort Fuchs, Hermann
collection PubMed
description PURPOSE: To investigate the response of detectors for proton dosimetry in the presence of magnetic fields. MATERIAL AND METHODS: Four ionization chambers (ICs), two thimble‐type and two plane‐parallel‐type, and a diamond detector were investigated. All detectors were irradiated with homogeneous single‐energy‐layer fields, using 252.7 MeV proton beams. A Farmer IC was additionally irradiated in the same geometrical configuration, but with a lower nominal energy of 97.4 MeV. The beams were subjected to magnetic field strengths of 0, 0.25, 0.5, 0.75, and 1 T produced by a research dipole magnet placed at the room’s isocenter. Detectors were positioned at 2 cm water equivalent depth, with their stem perpendicular to both the magnetic field lines and the proton beam’s central axis, in the direction of the Lorentz force. Normality and two sample statistical Student’s t tests were performed to assess the influence of the magnetic field on the detectors’ responses. RESULTS: For all detectors, a small but significant magnetic field‐dependent change of their response was found. Observed differences compared to the no magnetic field case ranged from +0.5% to −0.7%. The magnetic field dependence was found to be nonlinear and highest between 0.25 and 0.5 T for 252.7 MeV proton beams. A different variation of the Farmer chamber response with magnetic field strength was observed for irradiations using lower energy (97.4 MeV) protons. The largest magnetic field effects were observed for plane‐parallel ionization chambers. CONCLUSION: Small magnetic field‐dependent changes in the detector response were identified, which should be corrected for dosimetric applications.
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spelling pubmed-82519092021-07-07 MR‐guided proton therapy: Impact of magnetic fields on the detector response Fuchs, Hermann Padilla‐Cabal, Fatima Zimmermann, Lukas Palmans, Hugo Georg, Dietmar Med Phys COMPUTATIONAL AND EXPERIMENTAL DOSIMETRY PURPOSE: To investigate the response of detectors for proton dosimetry in the presence of magnetic fields. MATERIAL AND METHODS: Four ionization chambers (ICs), two thimble‐type and two plane‐parallel‐type, and a diamond detector were investigated. All detectors were irradiated with homogeneous single‐energy‐layer fields, using 252.7 MeV proton beams. A Farmer IC was additionally irradiated in the same geometrical configuration, but with a lower nominal energy of 97.4 MeV. The beams were subjected to magnetic field strengths of 0, 0.25, 0.5, 0.75, and 1 T produced by a research dipole magnet placed at the room’s isocenter. Detectors were positioned at 2 cm water equivalent depth, with their stem perpendicular to both the magnetic field lines and the proton beam’s central axis, in the direction of the Lorentz force. Normality and two sample statistical Student’s t tests were performed to assess the influence of the magnetic field on the detectors’ responses. RESULTS: For all detectors, a small but significant magnetic field‐dependent change of their response was found. Observed differences compared to the no magnetic field case ranged from +0.5% to −0.7%. The magnetic field dependence was found to be nonlinear and highest between 0.25 and 0.5 T for 252.7 MeV proton beams. A different variation of the Farmer chamber response with magnetic field strength was observed for irradiations using lower energy (97.4 MeV) protons. The largest magnetic field effects were observed for plane‐parallel ionization chambers. CONCLUSION: Small magnetic field‐dependent changes in the detector response were identified, which should be corrected for dosimetric applications. John Wiley and Sons Inc. 2021-04-03 2021-05 /pmc/articles/PMC8251909/ /pubmed/33326614 http://dx.doi.org/10.1002/mp.14660 Text en © 2020 The Authors. Medical Physics published by Wiley Periodicals LLC on behalf of American Association of Physicists in Medicine. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle COMPUTATIONAL AND EXPERIMENTAL DOSIMETRY
Fuchs, Hermann
Padilla‐Cabal, Fatima
Zimmermann, Lukas
Palmans, Hugo
Georg, Dietmar
MR‐guided proton therapy: Impact of magnetic fields on the detector response
title MR‐guided proton therapy: Impact of magnetic fields on the detector response
title_full MR‐guided proton therapy: Impact of magnetic fields on the detector response
title_fullStr MR‐guided proton therapy: Impact of magnetic fields on the detector response
title_full_unstemmed MR‐guided proton therapy: Impact of magnetic fields on the detector response
title_short MR‐guided proton therapy: Impact of magnetic fields on the detector response
title_sort mr‐guided proton therapy: impact of magnetic fields on the detector response
topic COMPUTATIONAL AND EXPERIMENTAL DOSIMETRY
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251909/
https://www.ncbi.nlm.nih.gov/pubmed/33326614
http://dx.doi.org/10.1002/mp.14660
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