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Cooperation between a T Domain and a Minimal C‐Terminal Docking Domain to Enable Specific Assembly in a Multiprotein NRPS

Non‐ribosomal peptide synthetases (NRPS) produce natural products from amino acid building blocks. They often consist of multiple polypeptide chains which assemble in a specific linear order via specialized N‐ and C‐terminal docking domains ((N/C)DDs). Typically, docking domains function independent...

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Detalles Bibliográficos
Autores principales: Watzel, Jonas, Duchardt‐Ferner, Elke, Sarawi, Sepas, Bode, Helge B., Wöhnert, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251938/
https://www.ncbi.nlm.nih.gov/pubmed/33876501
http://dx.doi.org/10.1002/anie.202103498