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Cooperation between a T Domain and a Minimal C‐Terminal Docking Domain to Enable Specific Assembly in a Multiprotein NRPS
Non‐ribosomal peptide synthetases (NRPS) produce natural products from amino acid building blocks. They often consist of multiple polypeptide chains which assemble in a specific linear order via specialized N‐ and C‐terminal docking domains ((N/C)DDs). Typically, docking domains function independent...
Autores principales: | Watzel, Jonas, Duchardt‐Ferner, Elke, Sarawi, Sepas, Bode, Helge B., Wöhnert, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251938/ https://www.ncbi.nlm.nih.gov/pubmed/33876501 http://dx.doi.org/10.1002/anie.202103498 |
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