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Biochemical Investigation of the Interaction of pICln, RioK1 and COPR5 with the PRMT5–MEP50 Complex

The PRMT5–MEP50 methyltransferase complex plays a key role in various cancers and is regulated by different protein–protein interactions. Several proteins have been reported to act as adaptor proteins that recruit substrate proteins to the active site of PRMT5 for the methylation of arginine residue...

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Detalles Bibliográficos
Autores principales: Krzyzanowski, Adrian, Gasper, Raphael, Adihou, Hélène, Hart, Peter 't, Waldmann, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252068/
https://www.ncbi.nlm.nih.gov/pubmed/33624332
http://dx.doi.org/10.1002/cbic.202100079