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Neurofibrillary tau depositions emerge with subthreshold cerebral beta-amyloidosis in down syndrome
INTRODUCTION: Adults with Down syndrome are genetically predisposed to develop Alzheimer’s disease and accumulate beta-amyloid plaques (Aβ) early in life. While Aβ has been heavily studied in Down syndrome, its relationship with neurofibrillary tau is less understood. The aim of this study was to ev...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252122/ https://www.ncbi.nlm.nih.gov/pubmed/34182407 http://dx.doi.org/10.1016/j.nicl.2021.102740 |