Neurofibrillary tau depositions emerge with subthreshold cerebral beta-amyloidosis in down syndrome

INTRODUCTION: Adults with Down syndrome are genetically predisposed to develop Alzheimer’s disease and accumulate beta-amyloid plaques (Aβ) early in life. While Aβ has been heavily studied in Down syndrome, its relationship with neurofibrillary tau is less understood. The aim of this study was to ev...

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Detalles Bibliográficos
Autores principales: Zammit, Matthew D., Tudorascu, Dana L., Laymon, Charles M., Hartley, Sigan L., Ellison, Paul A., Zaman, Shahid H., Ances, Beau M., Johnson, Sterling C., Stone, Charles K., Sabbagh, Marwan N., Mathis, Chester A., Klunk, William E., Cohen, Ann D., Handen, Benjamin L., Christian, Bradley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252122/
https://www.ncbi.nlm.nih.gov/pubmed/34182407
http://dx.doi.org/10.1016/j.nicl.2021.102740

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