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A modified protocol for successful miRNA profiling in human precision-cut lung slices (PCLS)

OBJECTIVE: Human precision cut lung slices (PCLS) are widely used as an ex vivo model system for drug discovery and development of new therapies. PCLS reflect the functional heterogeneity of lung tissue and possess relevant lung cell types. We thus determined the use of PCLS in studying non-coding R...

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Detalles Bibliográficos
Autores principales: Niehof, Monika, Reamon-Buettner, Stella Marie, Danov, Olga, Hansen, Tanja, Sewald, Katherina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8252208/
https://www.ncbi.nlm.nih.gov/pubmed/34215333
http://dx.doi.org/10.1186/s13104-021-05674-w

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